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Julie Holland
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Also by Julie Holland

Weekends at Bellevue

Copyright

Thorsons

An imprint of HarperCollinsPublishers 1 London Bridge Street London SE1 9GF

www.harpercollins.co.uk

Published in the US by Penguin Press 2015

First published in the UK by Thorsons 2015

© Julie Holland 2015

A catalogue record of this book is available from the British Library

While every effort has been made to trace the owners of copyright material reproduced herein and secure permissions, the publishers would like to apologise for any omissions and will be pleased to incorporate missing acknowledgements in any future edition of this book.

Julie Holland asserts the moral right to be identified as the author of this work

All rights reserved under International and Pan-American Copyright Conventions. By payment of the required fees, you have been granted the nonexclusive, non-transferable right to access and read the text of this e-book on screen. No part of this text may be reproduced, transmitted, downloaded, decompiled, reverse engineered, or stored in or introduced into any information storage retrieval system, in any form or by any means, whether electronic or mechanical, now known or hereinafter invented, without the express written permission of HarperCollins e-books.

Find out about HarperCollins and the environment at www.harpercollins.co.uk/green

Source ISBN: 9780007554126

EBook Edition © MARCH 2015 ISBN: 9780007554133

Version: 2015-02-20

For Sara Starr Wolff, teacher, therapist, and gardener, who wanted what she had, and said what she meant. And for her son, Jeremy, whose shining love and acceptance allow me to blossom.

Contents

Cover

Title Page

Also by Julie Holland

Copyright

Dedication

Introduction

Part One Moody by Nature

One Own Your Moods

Two Bitchy Like Clockwork

Part Two Mating, MILFs, Monogamy, and Menopause

Three This Is Your Brain on Love

Four Marriage and Its Discontents

Five Motherhead

Six Perimenopause: The Storm Before the Calm

Part Three The Moody Bitches Survival Guide

Seven Inflammation: The Key to Everything

Eight Food: A Drug We Can’t Resist

Nine So Tired We’re Wired

Ten A Sex Guide That Actually Works

Eleven Your Body: Love It or Leave It

Twelve You. Need. Downtime.

Conclusion: Staying Sane in an Insane World

Appendix: Naming Names: A Guide to Selected Drugs

Notes

Glossary

List of Searchable Terms

Acknowledgments

About the Publisher

Introduction

Women today are overworked and exhausted. We are anxious and frazzled, yet depressed and burned out. Our moods and libidos are at a rock-bottom low, our vital energies drained as we struggle to keep up with work, family, and hundreds of “friends” online. We blame ourselves for how bad we feel, thinking we should be able to handle it all. We dream of being perfect; we even try to make it look effortless, but we were never meant to be so static. We are designed by nature to be dynamic, cyclical, and, yes, moody. We are moody bitches, and that is a strength—not a weakness.

We evolved that way for good reasons; our hormonal oscillations are the basis for a sensitivity that allows us to be responsive to our environment. Our dynamism imparts flexibility and adaptability. Being fixed and rigid does not lend itself to survival. In nature, you adapt or you die. There is tremendous wisdom and peace available to us if we learn how our brains and bodies are supposed to work. Moodiness—being sensitive, caring deeply, and occasionally being acutely dissatisfied—is our natural source of power.

Yet we have been told just the opposite. From a young age, we are taught that moodiness, and all that comes with it, is a bad thing. We learn to apologize for our tears, to suppress our anger, and to fear being called hysterical. Over the course of women’s lives, the stresses and expectations of the modern world interfere with our health and hormones in ways big and small, and the result is the malaise so many women feel. There simply is a better way.

Moody Bitches opens the playbook on how we can take hold of our moods and, in so doing, take hold of our lives. By integrating timeless wisdom with today’s science, we can master our moods. If we can understand our own bodies, our naturally cycling hormones, and how modern medicines derange our exquisitely calibrated machines, then we can make informed choices about how to live better.

Women’s hormones are constantly in flux. They ebb and flow over a month-long cycle and they wax and wane throughout decades of fertility, vacillating with particular volatility during adolescence and perimenopause, the spring and autumn of the reproductive years. Compare this to men’s stable hormone levels throughout most of their lives. Our hormonal variations allow us to be empathic and intuitive—to our environment, to our children’s needs, and to our partners’ intentions. Women’s emotionality is normal. It is a sign of health, not disease, and it is our single biggest asset. Yet one in four American women are choosing to medicate away their emotionality with psychiatric medications, and the effects are more far-reaching than most women realize.

Whether it’s food, alcohol, drugs, cell phones, or shopping, we all rely on something in order to numb ourselves during difficult times. Whatever the chosen substance, it offers a welcome promise: that things will be different and better once it is consumed. But you can never get enough of something that almost works, and because our solutions are usually synthetic, not natural, we come up short. We are uncomfortable in our own skin, with our own desires; we are not at ease in our homes and offices, in our roles as parents or caretakers of our parents. Plowing forward, we think we can outrun the angst if we just stay “insanely busy.”

In my psychiatric practice, my patients, like most women, are starved for information about the drugs they’re taking and how they can change how they’re feeling. Moody Bitches is an answer to both problems. I name names (which medicines I love, and the ones I avoid) and discuss the real side effects I’ve observed—weight gain, libido loss, becoming blasé—and what you can do about them. I share straight talk about enhancing your sex life, the direct link between food and mood, sticking to exercise or sleep schedules, and perhaps the most important piece: tuning in to your body to realign with your natural, primal self.

When I started my practice twenty years ago, women came to me confused by their symptoms and unsure of what to do. They complained of difficulty getting back to sleep or agitation or tearfulness, but they didn’t quite know what was wrong. I helped them put a name to their symptoms and explained that there were medicines that could help. I needed to do more teaching about drug therapy back then, and a lot more hand-holding. I would set aside the last ten or fifteen minutes of the hour-long initial consultation in order to quell the fears of people who were wary of taking something that would alter their brain chemistry.

These days, new patients come to me sure that they need medicine for their nerves or their moods, like most of the other women they know. They want me only to help them figure out which one. The confusion used to be: “I can’t understand why I keep waking up at four in the morning”; “It’s so hard to get out of bed and I don’t really care about anything”; “I’m angry all the time, and I don’t know why.” But over the years, the conversation has morphed, so that now it usually begins with something like this: “Can you tell me the difference between bupropion and venlafaxine?”; “I can’t figure out if I have ADD or OCD”; “Do you know that ad with the woman riding the horse on the beach?”; “Is that new butterfly sleeping pill better than zolpidem?” And the one I hear more than you can imagine from my established patients: “Is there anything new I can try?”

The drug companies started direct-to-consumer advertising in the 1980s. Soon after I started my private practice in the mid-1990s, it became less heavily regulated. Ads started springing up on television and in magazines, trumpeting the latest antidepressants and sleeping pills. I went along for the ride as America’s use of all prescription psychiatric medications tripled during the nineties, as a direct result of this powerful marketing. By 2006 the antidepressant Zoloft (sertraline) had made more money than Tide detergent, and it became clear to me that something new was happening. Drug companies are spending billions of dollars to turn normal human experiences like fear or sadness into medical diseases. They aren’t developing cures; they’re creating customers. The problem is not our emotionality; the problem is that we are being persuaded to medicate it away.

The latest news is particularly terrifying. Aripiprazole, a medicine originally formulated to treat people with schizophrenia, expanded into the depression market and is now our nation’s top-selling medication, and not just of psych meds. America’s number one moneymaking medicine is an antipsychotic. As a psychiatrist, I must tell you, this is insane. There is an ancient Greek word, pharmakon, which held disparate meanings—sacrament, medicine, and poison. It is a common saying in medicine that sometimes the treatment is worse than the disease. There are many medications (chemotherapy is a good example) that are helpful or curative at lower doses but dangerously toxic in higher amounts. It is also true that there are powerful medicines that are appropriately used for one diagnosis but are complete overkill for another. Prescribing antipsychotics to treat depression seems particularly out of balance, especially given the risks of irreversible side effects like diabetes or movement disorders inherent in this class of medicine.

We represent 5 percent of the global population, yet we take 50 percent of the world’s pills. (We also take 80 percent of the world’s painkillers.) Meanwhile, the percentage of people labeled with psychiatric diagnoses is continually growing. Is it possible there really is an epidemic of mental illness and disability happening in our lifetime, or are physicians too quick to reach for their prescription pads instead of offering harder solutions to their patients’ complaints? Medical journals are full of only one kind of ad: pages of information on the newest drugs and exactly how to prescribe them. Four out of five prescriptions for antidepressants are not even written by psychiatrists but rather by general practitioners, and more often than not they’re prescribed for patients without an actual diagnosis of depression. Particularly troubling: surveys of primary care doctors show they routinely overestimate what the antidepressants can do. They’ve been hoodwinked by the ads, like the rest of America.

Just as offering your toddler the choice between the red dress and the blue dress moves the conversation forward, beyond “you need to wear a dress,” the barrage of antidepressant advertising advances the question from Should I take an antidepressant? to Which one should I take? Don’t let pharma-con change the way you manage your moodiness. I’m here to tell you that there are healthier ways to treat depression, anxiety, and irritability that don’t include pills.

It is not solely the right cocktail of neurotransmitters that dictates mood; more than anything, it is how we live our lives. We can improve how we feel by changing behaviors around food, sex, exercise, addictions, and work/family balance. The problem with taking your happy pills and puttering along as before is that it’s no better than sweeping dirt under the carpet. I want you to take that rug out back and beat the hell out of it.

But this is not drudgery. It begins with awareness, with the natural process of reconnecting with yourself and your body. Understanding the meaning and utility of your moods is empowering. Reclaiming your authentic, natural self is liberating. It is wholesome and it is healing. Not just for you, but also for your partner, your family, and your community.

This book begins with information about our complex inner workings, revealing the science behind why, as caregivers and nurturers, women have evolved to think and feel differently from men. I explain the wisdom of feeling deeply, and the dangers of cutting ourselves off from that depth. I look closely at why the twenty-eight-day cycle brings on tears and insatiable hunger (and what you can do about it), and how oral contraceptives and antidepressants can disrupt natural phases of desire and connection, potentially leading you to choose “Mr. Wrong,” or even to opt out of any mate choice entirely.

The second section delves into relationships and family, with a particular focus on how women’s moods mirror critical transition points in our lives. From menarche (the very first menstrual cycle) to mating, from motherhood to menopause, our ever-fluctuating hormones not only dictate but also respond to our behaviors. Testosterone may make you horny to go out and find a guy, but, more likely, seeing a hot new guy will make your testosterone levels rise. We tend to think of love and sex as distinct, but falling head over heels is a physical experience as powerful as any mind-altering drug, and orgasmic sex can trigger hormones that change how attached you are to your partner, complicating your casual hookups. The early stages of a relationship are difficult enough to navigate, but long-term commitment poses its own complications. Moody Bitches tells the truth about monogamy and desire, and why it is that your SSRI (anti-depressants like paroxetine or sertraline) is likely not doing you any favors in the bedroom. I also explain the physical and emotional consequences of pregnancy and child rearing; becoming a mother changes not just your body but your brain.

Change is the constant in women’s lives, and never more so than in perimenopause, the transitional period before fertility ends that recalls the turmoil of pubescence. Moody Bitches unpacks the biology behind the “cougar” stereotype, describes the herbs and supplements that can combat hot flashes, and paves the way for the peace and freedom that await on the other side.

The third section, the Moody Bitches Survival Guide, is an instruction manual for well-being at any age. We begin with a comprehensive introduction to inflammation, the basis of nearly every medical disease, including depression. Stress and inflammation are inextricably linked, and the key to combating both lies in a system you’ve probably never heard of, the endocannabinoid system. When stress nearly knocks you overboard, your internal cannabinoid system helps to right the ship. Even if you’ve never smoked a joint, your brain and body use cannabis-like molecules to make you resilient to stress, similar to the way your endorphin system provides you with natural pain relief. These cannabinoids tamp down inflammation and reactivity in the body, maintaining metabolism, immune functioning, learning, and growing. The endocannabinoid system is mentioned throughout Moody Bitches, because it is involved in nearly everything we do, like eating, sleeping, exercising, having sex, giving birth, and nursing.

The practices detailed in the survival guide are critical tools for establishing and preserving mental and physical health; they are designed to reduce stress and inflammation and augment the body’s own spectacular capacity for producing pleasure. You’ll learn about natural nutrition, so you can stop dieting and start eating for health, and normal sleep, so you can prioritize the hours your body needs. In fact, better sleep, nutrition, and regular cardio in the sunshine may just replace your SSRI. The survival guide also includes practical advice on sex that actually works and addresses the main obstacles women face in reaching orgasm. Getting into and enjoying your body, whether through sex, exercise, or that dreaded word mindfulness, will help you achieve the balance and harmony we’re all clamoring for.

Moody Bitches is a rallying cry for a new way of living. Our lives are out of sync with nature. I fear that the further away we get from what’s natural for us, the sicker we’re going to get. Our disconnection is our pathology. We need to get back in tune with our bodies and with the natural world around us. In our digital distraction we’ve lost a basic truth: fresh air, sunlight, and movement make us feel better. Daily cycles of light and dark will do more for our sleep than any pill, being sedentary is our biggest health hazard, and we miss a lot when our relationships become virtual.

Moody Bitches is grounded in research and informed by my experiences in working with my patients. Health begins with understanding, and my aim is to demystify women’s inner lives to enable change. I’m speaking as a psychiatrist, a wife, and a working mother of two children; the prescriptions I share here are what have worked for me, and for my patients.

Our bodies are wiser than we ever imagined, and so much of what plagues them is interrelated. Overmedication has robbed us of our sense of control, and modern life has separated us from the restorative rhythms of nature. It is understandable to respond to the man-made madness of this world with tears and frustration; those feelings of distress are a pathway toward health and wholeness. We need to tune in to our discomfort, not turn it down. Being sensitive, being irritated, and being vocal about our needs and frustrations will improve our lives.

Once we begin to listen to our bodies and align with our moodiness, we can take action. That action might be to try a natural remedy when you had relied on a prescription. It might be to reappraise all that you ask of yourself in your many roles as a woman. The answer for each of us will be unique. But all of us need to stop and listen when we get bitchy. Embracing our moods will, in the end, make us happier.

We need to begin anew, to realign with our bodies and learn how to treat them right. It’s time to embody the wisdom inherent in nature, and in our natural animal selves. Moody Bitches will show you the way, giving you the tools you need to take care of yourself.

Part One

Moody by Nature

One

Own Your Moods

While I spend most of my workday having one-on-one sessions with my patients, I’ve made several television appearances as a psychiatric expert over the years. One afternoon not long ago I sat down across from a newswoman in the studio. We were chatting before we rolled tape. She seemed pert, energetic, and emotionally connected. We hit it off immediately and were enjoying the hushed banter that ensues before taping; then I noticed her fingernails were bitten down quite a bit. When I asked her about it, she told me her therapist had consistently recommended she take medication to “calm her nerves,” but she was resistant to the idea.

“I bet your anxiety helps you in your work,” I offered. “You have to be hyperaware to know what’s a good story to cover, and perceptive about when and how to push certain questions during an interview. Also, I would guess you have some obsessive traits that help you stay organized and productive, leaving no stone unturned.”

She looked at me like I truly understood her. “Yes.” She stared at me, dumbfounded. “Yes!” she repeated. “It’s also just who I am: I am nervous, jumpy. I’ve always been like this. Why would I want to medicate away my own basic personality?”

Why indeed?

More women than ever before are taking psychiatric medications, creating a new normal that isn’t normal at all. It is at odds with our biology. Our brains are wired differently from men’s brains, and our hormones do make us more moody.

Women feel more, and for good reasons. By evolutionary design, women’s brains have developed to encourage empathy, intuition, emotionality, and sensitivity. We are the caretakers and the life givers; our ability to recognize and respond to the needs and moods of others is key to their and our survival, the basis of family, community, and connection. We need to intuit when our children are in danger or in need, or when the men around us might have malevolent intent. We will subordinate when that’s safest, but we will also aggressively protect those in our charge, whether family or friends.

Women have always been asked to do difficult work, and our bodies have powerful coping mechanisms to meet these challenges. But living with mechanisms like moodiness and acute sensitivity can be a trying experience on a daily basis. If that weren’t enough, like the newswoman I met on set, we are all under constant pressure to restrain our emotional lives and our natural strengths.

The Altered States of America: One Nation, Feeling Like Crap

It’s not just that our hormones make us more moody. It’s also that the pharmaceutical industry has exploited this biological attribute through advertising. Antidepressants are overwhelmingly marketed to women, stigmatizing depression as a feminine illness, making men less likely to seek treatment, and giving women the go-ahead to take their daily dose so they can cook for their families and dote on their children. Ads for antidepressants (and antipsychotics used to treat depression) are commonplace in women’s magazines like Good Housekeeping and Better Homes and Gardens, and on daytime talk shows. They typically feature pictures of women with sad faces, staring out the window, unable to play with their neglected, frowning children or text their friends. (I wish I were kidding about this last one. The “after” picture for one antidepressant shows a woman now on meds, happily texting someone on her phone.) Many ads now encourage a woman to ask her doctor to consider adding an antipsychotic into the mix after a mere six-week trial of her antidepressant has “failed.”

While the number of Americans on antidepressants has skyrocketed year after year, two big bumps are seen historically. The first was when direct-to-consumer advertising broadened in 1997, completely orchestrated by the Big Pharma lobbies. The other jump in sales came after 9/11, when pharmaceutical marketing homed in on women even more. That September, the women I saw in my office were acutely anxious, fearful for the safety of their Wall Street husbands or their children who were in downtown elementary schools near the attack. They were tense, twitchy, and unable to sleep. Coincidentally, the makers of Paxil (paroxetine) came out with a print ad of a woman on a crowded city street, clutching her bag, jaw clenched, surrounded by words like “sleep problems” and “worry,” with the tagline “Millions could be helped by Paxil.” Drug makers appeared to have found 9/11 to be a marketing opportunity. Glaxo doubled its advertising to $16 million in October 2011, compared with the previous October’s $8 million. That’s just one month of advertising dollars to hook all the women who had a natural, fearful response to a terrorist act. And it paid off big. They got on their meds and stayed on them.

All of this direct-to-consumer advertising has given many of us, especially people who came of age in the 1990s, an inflated sense that we are lay psychopharmacologists. We’ve seen enough ads to know which medicines have lower incidences of sexual side effects (bupropion, an antidepressant that does not raise serotonin levels) and which ones report an increased risk of sudden death (aripiprazole, an antipsychotic prescribed for depression, when used in elderly dementia patients). My mother often said, “A little bit of knowledge is a dangerous thing.” Gen Xers are quick to stock up on pharmaceuticals garnered from friends, the Internet, and physicians, and dole them out to friends and family. As the New York Times explained, “they choose to rely on their own research and each other’s experience in treating problems like depression . . . a medical degree, in their view, is useful but not essential.”

At this point, everybody and their cat are on antidepressants. Seriously—one of my patients has an underweight cat that was recently prescribed mirtazapine, an antidepressant that can cause increased appetite. In today’s insurance-driven health-care system, handing over a prescription is the easiest, quickest way for doctors to get someone out of their office so they can see their next patient. It also keeps the patients coming back for easy, efficient refills. Unfortunately, shorter doctors’ visits, now the norm, mean more time spent alleviating symptoms with pills and less spent digging down to really fix the problem. There is simply no talking about the harder but healthier ways to treat the symptoms. Cholesterol-lowering medicines called statins are a good example. A doctor can spend twenty minutes trying to educate a patient about dietary changes and exercise that could lower cholesterol levels, or can hand over a prescription for a pill being pushed by every drug rep who comes to the office bearing a tray of cheese Danish.

Women are particularly vulnerable to overprescribing. Numerous medical chart reviews consistently show that doctors are more likely to give women psychiatric medications than men, especially women between the ages of thirty-five and sixty-four, who often present with complaints of nervousness, difficulty sleeping, sexual dysfunction, or low energy. A patient recently asked me if he should take Risperdal, an antipsychotic, for his nervousness, because his female colleague told him it had been helping her with anxious thoughts. Risperdal was originally formulated for use in schizophrenia, but people with schizophrenia make up only 1 percent of the world’s population. It’s obviously better business to target 50 percent of the population: women.

I’m not suggesting that all use of psychiatric medicines is counterproductive. People who don’t really need these meds are taking them, while people who are genuinely psychiatrically ill remain undiagnosed and untreated, often due to socioeconomic factors. Clearly there are times when we need to pull out the big guns. Vegetative depressions that last for weeks, when you can’t get out of bed, bathe, or feed yourself, are not going to resolve themselves through soul-searching. Manic episodes where there is no sleep to be had for many days in a row will require mood stabilizers. But we’ve gotten ourselves into a situation in America now where more women are taking antidepressants and antianxiety medications for years on end, and it’s lowering the bar for all of us, creating a new normal in terms of invulnerable posturing and emotional blunting, and, more important, it is changing the tipping point for when other women will seek chemical assistance.

Cosmetic psychopharmacology is not unlike cosmetic surgery. As more women get breast implants, the rest of us feel flat chested. And so it is with more women taking antidepressants and antianxiety medications. Suddenly, you’re the odd one out if you aren’t like your friends, taking something to “take the edge off ” or give you a little lift to withstand the slings and arrows on your journey. More women are feeling lousy and finding themselves on psychiatric medications, and staying on them far longer than they were ever meant to be used. And we’re not necessarily getting any better.

Made to Be Moody

As women, our interior lives are complex and ever changing. Our neurotransmitters and our hormones—estrogen in particular—are intricately linked. When estrogen levels drop, as in PMS, postpartum, or perimenopause, it’s common for moods to plummet as well. Waxing and waning levels of estrogen help us to be more emotional, allow us to cry more easily and even to break down when we’re overwhelmed. There are estrogen receptors throughout the brain that affect our mood and behavior, and there are complex back-and-forth interactions in the brain between estrogen and serotonin, the main neurotransmitter implicated in anxiety and depression. Although it’s more complicated than I’m making it out to be, it’s helpful to think of serotonin and estrogen as yoked. When one is up, the other is likely to be as well. So it is not your imagination. Where you are in your reproductive cycle, monthly and over your lifetime, is an enormous factor in determining what you are feeling.

Think of serotonin as the “it’s all good” brain chemical. Too high and you don’t care much about anything; too low and everything seems like a problem to be fixed. When serotonin levels are lower, as is seen in PMS, emotional sensitivity is heightened. We’re less insulated and end up more cranky, irritable, and dissatisfied. The most common antidepressants, also used to treat anxiety, are serotonin reuptake inhibitors (SSRIs). These are medicines (such as fluoxetine, sertraline, paroxetine, citalopram, and escitalopram) that block the brain’s natural recycling of the serotonin back into the nerve cell, so more can get across to the next neuron. If your serotonin levels are constantly, artificially high, you’re at risk of losing the emotional sensitivity that makes you you. You may be less likely to cry in the office or bite your nails to the quick, but you’re also going to have a harder time reacting emotionally and connecting fully with others, especially sexually.